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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HADHA
All Species:
38.48
Human Site:
S424
Identified Species:
76.97
UniProt:
P40939
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40939
NP_000173.2
763
83000
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
T
G
Chimpanzee
Pan troglodytes
XP_515339
763
82965
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
T
G
Rhesus Macaque
Macaca mulatta
XP_001086472
763
83034
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
T
G
Dog
Lupus familis
XP_532894
762
82917
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMS1
763
82651
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
I
G
Rat
Rattus norvegicus
Q64428
763
82646
S424
L
T
S
F
E
R
D
S
I
F
S
N
L
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508292
763
82918
S424
L
T
S
F
E
R
D
S
I
F
S
T
L
T
G
Chicken
Gallus gallus
NP_990387
770
83168
S431
L
T
S
F
E
R
D
S
I
L
S
N
M
T
A
Frog
Xenopus laevis
NP_001085618
760
82341
S421
V
T
S
F
E
R
D
S
I
V
T
N
L
T
G
Zebra Danio
Brachydanio rerio
NP_001082906
763
82870
T424
L
T
S
F
E
R
D
T
F
L
S
N
L
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609299
783
84056
Q436
I
S
A
L
E
R
D
Q
T
L
A
S
L
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192117
703
75892
R403
M
S
L
Q
G
L
A
R
G
E
Q
Q
V
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
89.6
N.A.
86.5
85.1
N.A.
85.5
77.2
77.4
72.3
N.A.
54.6
N.A.
N.A.
59.5
Protein Similarity:
100
99.8
99.3
95.1
N.A.
94
93.5
N.A.
92.4
87.9
89.2
84.8
N.A.
71.3
N.A.
N.A.
72.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
80
80
80
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
86.6
N.A.
60
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
92
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
84
0
0
0
0
9
59
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
75
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
9
9
0
9
0
0
0
25
0
0
84
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
92
0
9
0
0
0
0
0
9
0
% R
% Ser:
0
17
84
0
0
0
0
75
0
0
75
9
0
0
0
% S
% Thr:
0
84
0
0
0
0
0
9
9
0
9
9
0
67
0
% T
% Val:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _